Rupestonic Acid Derivative YZH-106 Promotes Lysosomal Degradation of HBV L- and M-HBsAg via Direct Interaction with PreS2 Domain
Hepatitis B surface antigen (HBsAg) is not only the biomarker of hepatitis B virus (HBV) infection and expression activity in hepatocytes, but it also contributes to viral specific T Head Phone Board Connect Wire cell exhaustion and HBV persistent infection.Therefore, anti-HBV therapies targeting HBsAg to achieve HBsAg loss are key approaches for a